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  • 标题:In vivo effects of antibodies to immune response gene products: prevention of experimental allergic encephalitis
  • 本地全文:下载
  • 作者:L Steinman ; J T Rosenbaum ; S Sriram
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1981
  • 卷号:78
  • 期号:11
  • 页码:7111-7114
  • DOI:10.1073/pnas.78.11.7111
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Prevention of experimental allergic encephalitis in SJL/J [H-2s] mice was achieved with in vivo administration of antibody reactive with I-As gene products prior to immunization with spinal cord antigen. No protection was evident in animals that received antisera specific for I-Js gene products. Administration of antibody to I-As beginning 5 days after immunization with spinal cord antigen delayed, but did not prevent, the onset of experimental allergic encephalitis.
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