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  • 标题:Sequence homologies in the 5' regions of four Drosophila heat-shock genes
  • 本地全文:下载
  • 作者:R Holmgren ; V Corces ; R Morimoto
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1981
  • 卷号:78
  • 期号:6
  • 页码:3775-3778
  • DOI:10.1073/pnas.78.6.3775
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:We report nucleotide sequences of the regions surrounding the 5' ends of the genes for Drosophila melanogaster heat-shock proteins hsp83, hsp68, and hsp26, located at chromosome positions 63BC, 95D, and 67B, respectively. As in other eukaryotic genes, the sequence T-A-T-A-A-A-A-T occurs about 30 nucleotides upstream from the sites of mRNA initiation. Three additional sequence homologies and a dyad symmetry were noted at approximately corresponding locations in the three genes and in the gene for another heat-shock protein, hsp70. We also found an intron near the 5' end of the hsp83 gene, with sequences at its boundaries typical of splice sites found in other organisms.
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