期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:1981
卷号:78
期号:8
页码:5076-5080
DOI:10.1073/pnas.78.8.5076
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:Molecules of adenovirus 2 DNA were isolated as nucleoprotein complexes late in infection of HeLa cells and examined by electron microscopy. Some were interpreted as representing intermediates in recombination events. The structures observed were consistent with predicted intermediates according to the model for genetic recombination proposed by Meselson and Radding [Meselson, M. S. & Radding, C. M. (1975) Proc. Natl. Acad. Sci. USA 72, 358-361] and constitute physical evidence from animal cells in support of this model.