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  • 标题:Human nucleolus organizers on nonhomologous chromosomes can share the same ribosomal gene variants
  • 本地全文:下载
  • 作者:M Krystal ; P D'Eustachio ; F H Ruddle
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1981
  • 卷号:78
  • 期号:9
  • 页码:5744-5748
  • DOI:10.1073/pnas.78.9.5744
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:The distributions of three human ribosomal gene polymorphisms among individual chromosomes containing nucleolus organizers were analyzed by using mouse--human hybrid cells. Different nucleolus organizers can contain the same variant, suggesting the occurrence of genetic exchanges among ribosomal gene clusters on nonhomologous chromosomes. Such exchanges appear to occur less frequently in mice. This difference is discussed in terms of the nucleolar organization and chromosomal location of ribosomal gene clusters in humans and mice.
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