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  • 标题:Evidence for a major cluster of lymphocyte differentiation antigens on murine chromosome 2
  • 本地全文:下载
  • 作者:D Meruelo ; M Offer ; A Rossomando
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1982
  • 卷号:79
  • 期号:23
  • 页码:7460-7464
  • DOI:10.1073/pnas.79.23.7460
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:The region of chromosome 2 between H-13 and H-3 has been shown to contain loci coding for a variety of other alloantigens, including Ly-4 and the locus coding for beta 2-microglobulin. Herein we show that Ly-6 and Ly-11 are coded for by genes in a segment of chromosome 2 adjacent to the H-3-H-13 region and that this segment of chromosome also contains the tightly linked loci coding for antigens Ala-1, DAG, H9/25, H-30, Ly-8, and ThB. In addition, at least one locus (and probably more) affecting susceptibility to leukemia induction is found within this gene cluster.
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