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  • 标题:Flagellar determinants of bacterial sensitivity to χ-phage
  • 本地全文:下载
  • 作者:Aravinthan D. T. Samuel ; Thomas P. Pitta ; William S. Ryu
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1999
  • 卷号:96
  • 期号:17
  • 页码:9863-9866
  • DOI:10.1073/pnas.96.17.9863
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Bacteriophage {chi} is known to infect motile strains of enteric bacteria by adsorbing randomly along the length of a flagellar filament and then injecting its DNA into the bacterial cell at the filament base. Here, we provide evidence for a "nut and bolt" model for translocation of phage along the filament: the tail fiber of {chi} fits the grooves formed by helical rows of flagellin monomers, and active flagellar rotation forces the phage to follow the grooves as a nut follows the threads of a bolt.
  • 关键词:Escherichia coli ; Salmonella typhimurium ; phage infection ; flagellar rotation
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