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  • 标题:IL-18 binding and inhibition of interferon γ induction by human poxvirus-encoded proteins
  • 本地全文:下载
  • 作者:Yan Xiang ; Bernard Moss
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1999
  • 卷号:96
  • 期号:20
  • 页码:11537-11542
  • DOI:10.1073/pnas.96.20.11537
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Molluscum contagiosum virus (MCV) is a common, human poxvirus that causes small papular skin lesions that persist for long periods without signs of inflammation. Previous studies revealed that MCV encodes a family of proteins with homology to mammalian IL-18 binding proteins. IL-18 is a proinflammatory cytokine that induces synthesis of interferon {gamma
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