标题:Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1β are differentially regulated in human blood mononuclear cells and mouse spleen cells
期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:1999
卷号:96
期号:5
页码:2256-2261
DOI:10.1073/pnas.96.5.2256
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:Interleukin (IL)-18, formerly called interferon {gamma} (IFN-{gamma})-inducing factor, is biologically and structurally related to IL-1{beta}. A comparison of gene expression, synthesis, and processing of IL-18 with that of IL-1{beta} was made in human peripheral blood mononuclear cells (PBMCs) and in human whole blood. Similar to IL-1{beta