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  • 标题:Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1β are differentially regulated in human blood mononuclear cells and mouse spleen cells
  • 本地全文:下载
  • 作者:Adrian J. Puren ; Giamila Fantuzzi ; Charles A. Dinarello
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1999
  • 卷号:96
  • 期号:5
  • 页码:2256-2261
  • DOI:10.1073/pnas.96.5.2256
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Interleukin (IL)-18, formerly called interferon {gamma} (IFN-{gamma})-inducing factor, is biologically and structurally related to IL-1{beta}. A comparison of gene expression, synthesis, and processing of IL-18 with that of IL-1{beta} was made in human peripheral blood mononuclear cells (PBMCs) and in human whole blood. Similar to IL-1{beta
  • 关键词:cytokines ; caspase 1 ; monocytes ; macrophages ; interferon γ
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