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  • 标题:Performing Arm-Based Network Meta-Analysis in R with the pcnetmeta Package
  • 本地全文:下载
  • 作者:Lifeng Lin ; Jing Zhang ; James S. Hodges
  • 期刊名称:Journal of Statistical Software
  • 印刷版ISSN:1548-7660
  • 电子版ISSN:1548-7660
  • 出版年度:2017
  • 卷号:80
  • 期号:1
  • 页码:1-25
  • DOI:10.18637/jss.v080.i05
  • 语种:English
  • 出版社:University of California, Los Angeles
  • 摘要:Network meta-analysis is a powerful approach for synthesizing direct and indirect evidence about multiple treatment comparisons from a collection of independent studies. At present, the most widely used method in network meta-analysis is contrast-based, in which a baseline treatment needs to be specified in each study, and the analysis focuses on modeling relative treatment effects (typically log odds ratios). However, populationaveraged treatment-specific parameters, such as absolute risks, cannot be estimated by this method without an external data source or a separate model for a reference treatment. Recently, an arm-based network meta-analysis method has been proposed, and the R package pcnetmeta provides user-friendly functions for its implementation. This package estimates both absolute and relative effects, and can handle binary, continuous, and count outcomes.
  • 关键词:absolute effect;arm-based method;Bayesian inference;network meta-analysis
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