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  • 标题:Validation of a Method for Simultaneous Determination of Acetaminophen and Caffeine by HPLC in Different Pharmaceutical Forms: Tablet, Capsule and Sachet
  • 本地全文:下载
  • 作者:Radi M. ; Ramli Y. ; El Karbane M.
  • 期刊名称:Journal of Materials and Environmental Science
  • 印刷版ISSN:2028-2508
  • 出版年度:2016
  • 卷号:7
  • 期号:12
  • 页码:4608-4613
  • 出版社:University of Mohammed Premier Oujda
  • 摘要:A simple, fast, economical, accurate, precise and reproducible RP – HPLC method was developed for thesimultaneous estimation of acetaminophen (AAPH) and caffeine (CAF) in starting materialand pharmaceuticaldosage forms. The method was validated in terms of specificity, linearity, precision accuracy, and robustness. Theproposed method’s results were found to be satisfactory and are suitable for determination of acetaminophen andcaffeine for routine quality control of drugs in formulations.
  • 关键词:acetaminophen; caffeine; HPLC; validation
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