摘要:Valorisation of grape marc, is a refuse of grape processing factories revealing each year in tons, is gaining an economic importance for the Turkey which has a significant position in viticulture for many years. In this manner, grape seed oil has become a popular product for food, pharmaceutical and cosmetic industries due to its rich bioactive components. Although, the cold press method is the most used one for the grape seed oil extraction as both being innocuous for oil constituents and having low cost; limited yield of this method lead to progress various methods (solvent assisted, supercritic liquid assisted, microwave assisted, ultrasound assisted, enzyme assisted etc.) which are able to carry out higher extraction yields so far. In this review, the advantages and disadvantages of important methods used for grape seed oil extraction were discussed in detail.