期刊名称：Journal of Theoretical and Applied Information Technology
印刷版ISSN：1992-8645
电子版ISSN：1817-3195
出版年度：2017
卷号：95
期号：6
出版社：Journal of Theoretical and Applied
摘要：This paper aims to develop a modular schema database for gene-associated diseases incidence in Indonesia, which is called as Genomic Medicine Research Group Database (GMRGDB). A modular architecture is beneficial to facilitate any manipulation and addition of new genes-affiliated diseases in the future. Currently, GMRGDB contains two categories, N-acetyltransferase 2 (NAT2) and Human Leukocyte Antigen (HLA) databases. NAT2 database is a repository of NAT2 genes and anti-TB drugs association, while HLA database records diseases related to Human Leukocyte Antigen. GMRGDB consists of patients� information from various ethnics in Indonesia, such as Javanese, Melayu, Betawi, Sundanese, and Batak. Users can view a number of samples for each database, detailed representation of Single Nucleotide Polymorphism (SNP), and also filter the data for specified ethnic through GMRGDB browser.
关键词：Genes-Associated Disease; Modular Database; N-Acetyltransferase 2; Human Leukocyte Antigen; Indonesian Ethnics
