Health Science university libraries represent the vast majority of health professionals and most accessible clinical information resources and services. The role of the library professional is emerging in quality improvement programs that use the information to assist health professionals in improving clinical practices at the point of care. A study was conducted to know the approaches to use of clinical information by medical students from the library in ten Health Science Universities / Deemed Universities located in the Karnataka state, for this purpose researcher chosen questionnaire methods and data gathered form 782 medical students. The result of the study shows that majority of the students from various deemed universities are well utilising the library for their clinical information needs and the researcher gives some suggestions and recommendations that still there is need to improve the infrastructure for more beneficial for the medical students provided by the university libraries.