期刊名称：International Journal of Mathematics and Mathematical Sciences
印刷版ISSN：0161-1712
电子版ISSN：1687-0425
出版年度：2017
卷号：2017
DOI：10.1155/2017/4804897
出版社：Hindawi Publishing Corporation
摘要：Tungiasis is a permanent penetration of female sand flea “Tunga penetrans” into the epidermis of its host. It affects human beings and domestic and sylvatic animals. In this paper, we apply optimal control techniques to a Tungiasis controlled mathematical model to determine the optimal control strategy in order to minimize the number of infested humans, infested animals, and sand flea populations. In an attempt to reduce Tungiasis infestation in human population, the control strategies based on personal protection, personal treatment, educational campaign, environmental sanitation, and insecticidal treatments on the affected parts as well as on animal fur are considered. We prove the existence of optimal control problem, determine the necessary conditions for optimality, and then perform numerical simulations. The numerical results showed that the control strategy comprises all five control measures and that which involves the three control measures of insecticide control, insecticidal dusting on animal furs, and environmental hygiene has the significant impact on Tungiasis transmission. Therefore, fighting against Tungiasis infestation in endemic settings, multidimensional control process should be employed in order to achieve the maximum benefits.
