出版社：International Medical Journal Management and Indexing System
摘要：Trichotillomania can be described as a psychiatric disorder where a recurring hair pulling behaviour is observed in an individual. Neurobiological causes of this condition is still unclear. Because of this, definite solutions can not be presented in the treatment. Molecular genetic studies are of great importance for a better understanding of the etiology of trichotillomania and for the treatment of this disorder. As of today, our knowledge and information about trichotillomania is limited. The molecular analyzes made suggest that HOXB8, SAPAP3, DRD1, DRD4, SLC6A4 genes may be related to the disease. In this review, the psychological and physiological basis and classification of trichotillomania will be followed by genetic polymorphisms that are thought to be related to molecular genetic studies, animal studies and disorders of trichotillomania. We hope that this article will also guide to the further molecular studies that can be carried out in this subject.
