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  • 标题:Diagnostic Value of NT-pro BNP Biomarker and Echocardiography in Cardiac Involvements in Beta-thalassemia Patients
  • 本地全文:下载
  • 作者:Noor Mohammad Noori ; Alireza Teimouri ; Maryam Nakhaey Moghaddam
  • 期刊名称:International Journal of Pediatrics
  • 印刷版ISSN:2345-5047
  • 电子版ISSN:2345-5055
  • 出版年度:2017
  • 卷号:5
  • 期号:11
  • 页码:6077-6094
  • DOI:10.22038/ijp.2017.24951.2110
  • 语种:English
  • 出版社:Mashhad University of Medical Sciences
  • 其他摘要:Background N-terminal pro–B-type natriuretic peptide (NT-proBNP) is a marker to evaluate the cardiac involvement in thalassemia. We aimed to evaluate conventional and tissue Doppler echocardiography findings and its relation to plasma NT-pro BNP, Ferritin and Iron levels in beta-thalassemia patients. Materials and Methods This study performed on 164 participants equal of major beta- thalassemia patients (n=82), and controls (82 healthy children with normal cardiovascular status). The patients collected from outpatients after applied exclusion criteria. Blood samples were taken from participants in fasting to measure NT- pro BNP, Ferritin and Iron serum. Participants were under echocardiography by Pediatric cardiologist. The level of error considered as 0.05 for data analysis by SPSS version 20.0. Results NT- pro BNP, Iron, Ferritin, left S', left A', right A', EF, FS, left and right A/A'; right and left MPI were significantly different in patients group (P
  • 其他关键词:Children; Cardiac involvement; echocardiography; NT-pro BNP; Beta-Thalassemia
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