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  • 标题:Hydrolysable Tannins and Related Compound having Cytotoxic Activity of Geranium Wilfordii Maxim
  • 作者:Ping Li ; Luosha Zhao ; Youyou Du
  • 期刊名称:Advance Journal of Food Science and Technology
  • 印刷版ISSN:2042-4868
  • 电子版ISSN:2042-4876
  • 出版年度:2013
  • 卷号:5
  • 期号:3
  • 页码:255-257
  • DOI:10.19026/ajfst.5.3253
  • 出版社:MAXWELL Science Publication
  • 摘要:In order to exhibit moderate cytotoxic activity toward the human tumor cell lines including A-549, SK-OV-3, HT-1080, K562 and S180, the cytotoxicity-directed fractionation of Me OH extract of Geranium wilfordii Maxim led to the isolation of three hydrolyzed tannins and a related compound, Gallic acid (I), 1, 2, 3, 4, 6-penta-O-galloyl-&beta-D-glucopyranose (ll), chebulagic acid (Ⅲ) and chebulinic acid (IV), as active principles. They were shown to exhibit moderate cytotoxicity against cultured human tumor cell lines including A549, SK-OV-3, HT-1080, K562 and S180 in vitro.
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