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  • 标题:Four cases of equine motor neuron disease in Japan
  • 本地全文:下载
  • 作者:Naoki SASAKI ; Yui IMAMURA ; Akio SEKIYA
  • 期刊名称:Journal of Equine Science
  • 印刷版ISSN:1340-3516
  • 电子版ISSN:1347-7501
  • 出版年度:2016
  • 卷号:27
  • 期号:3
  • 页码:119-124
  • DOI:10.1294/jes.27.119
  • 出版社:Japanese Society of Equine Science
  • 摘要:

    In this study, fasciculation of the limbs and tongue was observed in four horses kept by a riding club. Neurogenic muscle atrophy was also observed in biopsy of pathological tissues. In addition, in two cases that subjected to autopsy, Bunina-like bodies of inclusion in the cell bodies of neurons in the spinal cord ventral horn were confirmed, leading to a diagnosis of equine motor neuron disease (EMND). Serum vitamin E concentrations varied between 0.3 and 0.4µg/ml, which is significantly lower than the levels in normal horses. Although lack of vitamin E is speculated to be a contributory factor for development of EMND, no significant improvement was observed following administration of vitamin E.

  • 关键词:Bunina;equine motor neuron disease;horse;vitamin E
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