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文章基本信息

  • 标题:‘Functional’ body composition: differentiating between benign and non-benign obesity
  • 作者:Manfred J Müller ; Anja Bosy-Westphal ; Martin Heller
  • 期刊名称:F1000 Biology Reports
  • 电子版ISSN:2051-7599
  • 出版年度:2009
  • 卷号:1
  • DOI:10.3410/B1-75
  • 出版社:Faculty of 1000 Ltd
  • 摘要:Recent body composition analyses, together with assessments of insulin resistance, aerobic fitness, and intima-media thickness of the common carotid artery, have shown that metabolically-benign obese subjects have a similar BMI, waist circumference, and subcutaneous abdominal fat compared with non-metabolically-benign obese subjects. Research has suggested that 25-30% of the obese population do not need either treatment or prevention of secondary disorders. Therefore, assessment of functional body composition should replace nutritional status-based risk assessments (such as the body mass index) in both metabolic research and clinical decision making. The concept of ‘functional’ body composition gives us a more sophisticated view on nutritional status, metabolism, endocrinology, and diseases. Knowledge of detailed body composition enables characterization of biomedical traits which will give functional evidence relating genetic variants.
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