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文章基本信息

  • 标题:Modeling complex neuropsychiatric disease with induced pluripotent stem cells
  • 作者:P Joel Ross ; James Ellis
  • 期刊名称:F1000 Biology Reports
  • 电子版ISSN:2051-7599
  • 出版年度:2010
  • 卷号:2
  • DOI:10.3410/B2-84
  • 出版社:Faculty of 1000 Ltd
  • 摘要:The study of neuropsychiatric diseases and the development of effective treatments have been limited by a lack of appropriate models. Induced pluripotent stem cells (iPSCs) represent a potentially limitless supply of patient-specific cells for the study of neuropsychiatric disorders. In this review, we will discuss the potential and limitations of iPSCs for the development of cell-based models of neuropsychiatric diseases and the identification of novel therapeutics.
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