文章基本信息

标题：Synthesis of Biheterocycles Containing Indole Nucleus and Their Antibacterial Activity
其他标题：Synthesis of Biheterocycles Containing Indole Nucleus and Their Antibacterial Activity
作者：S. Jain ; B. N. Reddy ; K. S. Rao 等
期刊名称：Journal of Scientific Research
印刷版ISSN：2070-0237
电子版ISSN：2070-0245
出版年度：2012
卷号：4
期号：1
页码：273
DOI：10.3329/jsr.v4i1.7821
语种：English
出版社：Rajshahi University
摘要：Indole-3-carboxaldehydes (1a-d) undergo condensation with ethyl cyanoacetate and malononitrile to give the acrylonitrile 2a-d and 3a-d which on reaction with hydrazine hydrate yield 3,5-diamino-5-hydroxy-4-(3-indolylmethylene)pyrazoles (4a-d) and 3-amino-5-hydroxy -4-(3-indolylmethylene)pyrazoles (5a-d), respectively. The new compounds were also screened for their antibacterial activity.Keywords: Indole-3-carboxaldehydes ; Active methylene compounds; Base; Hydrazine hydrate; Pyrazoles.© 2012 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.doi: http://dx.doi.org/10.3329/jsr.v4i1.7821 J. Sci. Res. 4 (1), 273-278 (2012)
关键词：Chemistry;Indole-3-carboxaldehydes; Active methylene compounds; Base; Hydrazine hydrat;; Pyrazoles