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  • 标题:Antioxidant and antidiabetic potential of Myrothamnus flabellifolius found in Botswana
  • 本地全文:下载
  • 作者:Tebogo E. Kwape ; Runner R.T. Majinda ; Padmaja Chaturvedi
  • 期刊名称:Cogent Biology
  • 电子版ISSN:2331-2025
  • 出版年度:2016
  • 卷号:2
  • 期号:1
  • 页码:1275403
  • DOI:10.1080/23312025.2016.1275403
  • 语种:English
  • 出版社:Taylor and Francis Ltd
  • 摘要:Abstract The total phenol content, antioxidant and antidiabetic activity of Myrothamnus flabellifolius (MF) were investigated. The study revealed 70% ethanol/water (EW70), 70% methanol/water (MW70) and methanol (Me) extracts to contain the highest phenol content, 350 mg GAE/g, 300 mg GAE/g and 250 mg GAE/g, respectively (GAE/g—Gallic Acid Equivalent per gram). MW70 exhibited the highest radical [diphenyl picryl hydrazine (DPPH) and 2, 2-Azobis-3-ethyl benzthiazoline-6-sulphonic acid (ABTS+)] scavenging power. About 70% ethanol/water exhibited the highest reducing power, hydrogen peroxide and nitric oxide scavenging activities. The results of antidiabetic activity showed EW70 to possess the highest α-amylase inhibitory effect. The α-glucosidase activity was inhibited by EW70, n-Butanol fraction and ethyl acetate fraction, respectively. The results of the study suggest MF as a beneficial natural medicine.
  • 关键词:Myrothamnus flabellifolius ; antioxidant ; antidiabetic
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