文章基本信息

标题：Blood Superoxide Dismutase and Catalase Activities in Women Affected with Breast Cancer
其他标题：Blood Superoxide Dismutase and Catalase Activities in Women Affected with Breast Cancer
作者：M Negahdar ; M Djalali ; H Abtahi 等
期刊名称：Iranian Journal of Public Health
印刷版ISSN：2251-6085
电子版ISSN：2251-6093
出版年度：2005
卷号：34
期号：3
页码：39-43
语种：English
出版社：Tehran University of Medical Sciences
摘要：Experimental and epidemiological evidences implicate the involvement of oxygen derived radicals in the pathogenesis of cancer development. Oxygen derived radicals are able to cause damage to membranes, mitochondria and macromolecules including proteins, lipids and DNA. Accumulation of DNA damages has been suggested to contribute to carcinogenesis. It would, therefore, be advantageous to pinpoint the effects of oxygen derived radicals in cancer development. We investigated superoxide dismutase (SOD) and Catalase (CAT) activities in the whole blood of 50 breast cancer (BC) patients and 50 healthy and age matched women. The rate of SOD and CAT activities in BC patients was significantly lower (P
关键词：Catalase; ROS