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  • 标题:Characterization of Vancomycin Resistant Enterococcus faecium
  • 其他标题:Characterization of Vancomycin Resistant Enterococcus faecium
  • 作者:M Talebi ; SS Eshraghi ; MR Pourshafie
  • 期刊名称:Iranian Journal of Public Health
  • 印刷版ISSN:2251-6085
  • 电子版ISSN:2251-6093
  • 出版年度:2007
  • 卷号:36
  • 期号:4
  • 页码:20-25
  • 语种:English
  • 出版社:Tehran University of Medical Sciences
  • 摘要:Background: To determine the species distribution, updated drug susceptibility patterns and genes conferring resistance in clini­cal vancomycin resistant enterococcal (VRE) isolates.Methods: Clinical enterococcal isolates collected during 7 months, from September 2005 to April 2006 from hos­pitalized pa­tients and outpatients were studied. Twenty five VRE were isolated from 450 enterococci samples (5.6%). VRE isolates were subjected to antibiotic susceptibility tests. Genotype of these isolates was determined by PCR.Results: All of the isolates were E. faecium and carried the vanA gene. Antibiotic susceptibility tests showed that the iso­lates were resistant to ampicillin 25(100%), ciprofloxacin 25(100%), gentamicin 24(96%), erythromycin 25(100%), tetracy­clin 10(40%) and chloramphenicol 2(8%).Conclusion: VRE strains were resistant to three antibiotics and were susceptible to new antibiotics linezolid and dalfopris­tin-quinupristin. Switching to treatment with these antibiotics would relieve the problem for a short time.
  • 关键词:Enterococcus faecium
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