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  • 标题:Prevalence of oral human papilloma virus in healthy individuals in East azerbaijan province of iran.
  • 其他标题:Prevalence of oral human papilloma virus in healthy individuals in East azerbaijan province of iran.
  • 作者:Sharareh Seifi ; Iraj Asvadi Kermani ; Roya Dolatkhah
  • 期刊名称:Iranian Journal of Public Health
  • 印刷版ISSN:2251-6085
  • 电子版ISSN:2251-6093
  • 出版年度:2013
  • 卷号:42
  • 期号:1
  • 页码:79-85
  • 语种:English
  • 出版社:Tehran University of Medical Sciences
  • 摘要:Human papilloma virus causes benign and malignant abnormalities in different part of the body. The link between high risk types of HPV and some anogenital and aerodigestive tract cancer is well established. Oral HPV infection plays a role in developing oropharyngeal squamous cell carcinoma. We studied the prevalence of oral HPV in healthy individuals and its relative risk factors.Saliva samples of 114 healthy subjects were collected for HPV DNA analysis. Volunteers completed questionnaires and signed a written consent. For data analysis descriptive statistic, chi square test and odds ratio was used.The frequency of oral HPV in healthy individuals was 6.1 %(seven participant).The most frequent type was HPV-18 in five of them. HPV-6 and HPV-66 each was detected in one case. Relation of oral HPV positivity to demographic features and risk factors was not statistically significant.The prevalence of oral HPV infection in our community is the same as many other communities of developing countries, stressing that HPV-18 were the dominant type.
  • 关键词:Human Papilloma Virus (HPV);Oral Cancer;Saliva
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