摘要:P. vivax malaria with suspected long incubation have been frequently observed mostly in the northwest part of Iran in the course of Malaria Control and Malaria Eradication Operations. A sero-epidemiological study of such cases which present the first symptom in early spring, before anopheles activities season, was carried out in 92 selected villages with a population of 38,726 in two near areas in Ramadan and Bijar, in the west part pf Iran. . The total number of 3553 blood samples for microscopical and indirect fluorescent antibody serological technique were collected in 12 weekly total surveillance in the- early months of the year 1973 and 1974. Altogether seven cases parasitologically (P. vivax) and 98 cases serologically (titers 1/20 to 1/640) positive were observed. . From seven parasitological positive cases three were serologically negative. These three cases as they occurred at the beginning of appearance of anopheles.