摘要:Background: Preconception interventions in infertile couples can increase the chance of pregnancy and lower its complications. The success in infertility treatment and achieving a successful pregnancy is of great importance among infertile couples compared to others.This study has tried to investigate necessary preconception interventions before beginning of infertility treatment cycle among infertile couples. Materials and Methods: This is a cross-sectional study of 268 individuals presenting to fertility clinics (Moshtagh and Shahid beheshty) across the city of Isfahan, Iran. Simple sampling method was used. Questionnaire and patients' medical records were used to collect data. Descriptive and analytic statistical methods and SPSS software were used for analysis. Results: The results showed that the interventions related to diseases treatment and prescription of folic acid before the beginning of infertility treatment were complete for most of the subject (47.06% and 79.9% respectively), but referral for genetics counseling had not been conducted in most of the cases (98.9%). Specific interventions in relation with the infertility treatment before beginning the treatment cycle had been conducted in 50% of the subjects. Conclusion: The results of this study showed a weakness concerning necessary preconception interventions before beginning of infertility treatment cycle in most of the studied subjects. With regard to the effect of preconception interventions on outcome of infertility treatment, and with consideration of high importance of pregnancy success in infertile couples, paying more attention to conduct this manner is necessary.