Muhammadiyah Universities in South Sulawesi face the challenges of competitiveness, quality of human resources and lecturer’s on Tridharma performance in the field of education and teaching, research and scientific publications, and dedication to the community and other support activities.

This research aims at reconstructing the development of intellectual capital through Al-Islam Kemuhammadiyaan values approach. So as to create good work behavior in order to support the university’s performance on Tridharma.

This research is a quantitative research with positivist approach. The research design used in quantitative research is an explanatory research using survey methods at 10 Muhammadiyah universities in South Sulawesi by distributing questionnaires to 154 lecturers, but that can be processed only 146 questionnaires. Primary data were then analyzed using Structural Equations Models (SEM) techniques and the program is Analysis of Moment Structure (AMOS).

The research findings are: (1) intellectual capital contribute significantly in supporting the lecturer’s work behavior of Muhammadiyah Universities in South Sulawesi. (2) intellectual capital does not contribute significantly in supporting the lecturer’s Tridharma performance of Muhammadiyah Universities in South Sulawesi. (3) work behavior contribute significantly in supporting lecturer’s performance of Muhammadiyah Universities in South Sulawesi.