摘要：Whether or not Borrelia burgdorferi can persist after conventional treatment with antimicrobials hasbeen a very controversial issue. Two recent studies took different approaches to try to answer thisquestion. In one, investigators showed that, in each of 22 instances in 17 patients with two consecutiveepisodes of culture-proved erythema migrans, the strains of B. burgdorferi were different based on theirgenotypes. This indicated that the repeat episodes were due to new infections rather than recrudescenceof the original infection. In another study, in which persistence of B. burgdorferi was assessed by usingxenodiagnosis, no viable B. burgdorferi were cultured from ticks fed on any of the patients. Therecontinues to be no evidence that viable B. burgdorferi persist in humans after conventional treatment withantimicrobials.
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