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文章基本信息

  • 标题:Recent treatment advances and novel therapeutic approaches in epilepsy
  • 作者:Enrique Serrano ; Andres M. Kanner
  • 期刊名称:F1000 Biology Reports
  • 电子版ISSN:2051-7599
  • 出版年度:2015
  • 卷号:7
  • 页码:1-9
  • DOI:10.12703/P7-61
  • 出版社:Faculty of 1000 Ltd
  • 摘要:Epilepsy is a chronic disorder affecting 50 million peopleworldwide [1–3]. It is characterized by recurrent seizuresdue to abnormal excessive and synchronous neuronalactivity in the brain [4]. The International League AgainstEpilepsy [ILAE] defines epilepsy as “a disease characterizedby an enduring predisposition to generate epilepticseizures and by the neurobiological, cognitive, psychological,and social consequences of this condition”. Thus,the impact of epilepsy is not only limited to the actualseizures but also inclusive of the effects of antiepilepticdrugs (AEDs) and other treatments and the psychosocial,psychiatric, cognitive and medical comorbidities associatedwith the seizure disorder [4].
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