文章基本信息
- 标题：Chemical Synthetic Platform for Chlorpromazine Oligomers That Were Reported as Photo-degradation Products of Chlorpromazine
- 本地全文：下载
- 作者：Taiki Kohiki ; Yusuke Nishikawa ; Tsubasa Inokuma 等
- 期刊名称：Chemical and Pharmaceutical Bulletin
- 印刷版ISSN：0009-2363
- 电子版ISSN：1347-5223
- 出版年度：2017
- 卷号：65
- 期号：12
- 页码：1161-1166
- DOI：10.1248/cpb.c17-00692
- 语种：English
- 出版社：The Pharmaceutical Society of Japan
- 摘要：
A synthetic platform for chlorpromazine (CPZ) oligomers, which could be generated via photo-reaction of CPZ, is essential to promote their biological and structural studies. In this paper, the first synthetic platform for CPZ oligomers is described. A photo-irradiation experiment of CPZ to confirm whether the structure of the CPZ dimer generated by the photo-irradiation was identical to that prepared by our synthetic method is also reported.
- 关键词：chlorpromazine (CPZ);chlorpromazine dimer;chlorpromazine trimer;chlorpromazine oligomer;photo-reaction;photosensitization
