文章基本信息
- 标题：Chiral Organocatalyzed Intermolecular Rauhut–Currier Reaction of Nitroalkenes with Ethyl Allenoate
- 本地全文：下载
- 作者：Shinobu Takizawa ; Makoto Sako ; Kenta Kishi 等
- 期刊名称：Chemical and Pharmaceutical Bulletin
- 印刷版ISSN：0009-2363
- 电子版ISSN：1347-5223
- 出版年度：2017
- 卷号：65
- 期号：11
- 页码：997-999
- DOI：10.1248/cpb.c17-00554
- 语种：English
- 出版社：The Pharmaceutical Society of Japan
- 摘要：
An enantioselective intermolecular Rauhut–Currier (RC) reaction of nitroalkenes with ethyl allenoate has been established with quinidine-derived β-isocupreidine. The present RC reaction afforded α-functionalized allenoates 3 in up to 94% yield with 59% enantiomeric excess (ee).
- 关键词：Rauhut–Currier reaction;chiral organocatalysis;nitroalkene;α-functionalized allenoate
