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  • 标题:Association of non-alcoholic fatty liverdisease and cardiometabolic risk factorswith early atherosclerosis in an adultpopulation in Southern Italy
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  • 作者:Carmelo Antonio Caserta ; Alfonso Mele ; Pasquale Surace
  • 期刊名称:Annali dell'Istituto Superiore di Sanita
  • 印刷版ISSN:0021-2571
  • 出版年度:2017
  • 卷号:53
  • 期号:1
  • 页码:77-81
  • DOI:10.4415/ANN_17_01_14
  • 出版社:Editrice Kurtis Srl
  • 摘要:Aim. The prevalence of risk factors for cardiovascular and metabolic diseases was investigatedin an adult population of the city of Cittanova, Southern Italy.Methods. The study was conducted among 992 randomly selected adults aged 18-75years, between April 2009 and January 2011.Results. Prevalence rates of non-alcoholic fatty liver disease (NAFLD), overweight, obesity,and metabolic syndrome (MS) were 24.8%, 41.5%, 27.1%, and 34.4%, respectively.For the components of MS, prevalence of central obesity was 47.4%, impaired fastingglucose (IFG) 34.7%; hypertension 53.7%, low high-density lipoprotein (HDL) cholesterol34.2%, and hypertriglyceridemia 27.2%.Conclusions. Hypertension, central obesity, IFG, low HDL cholesterol, hypertriglyceridemia,MS, and increased carotid artery intima-media thickness (IMT) were significantlyassociated with NAFLD after adjustment for age and sex. With additionaladjustment for body mass index (BMI), IMT and MS (depending on the prevalence ratiothat was investigated), the positive association between the NAFLD and increasedIMT lost statistical significance, while that with body mass index (BMI) and MS remainedsignificant.
  • 关键词:obesity; NAFLD; metabolic syndrome; cardiovascular risk;factors; IMT
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