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  • 标题:Does Low-Dose Heparin Have a Significant Role in Free Flap Surgery?
  • 本地全文:下载
  • 作者:An, Mun-Young ; Shin, Jin Yong ; Lee, Young-Keun
  • 期刊名称:Archives of Craniofacial Surgery
  • 印刷版ISSN:2287-1152
  • 出版年度:2017
  • 卷号:18
  • 期号:3
  • 页码:162-165
  • DOI:10.7181/acfs.2017.18.3.162
  • 语种:English
  • 出版社:KoreaMed Synapse
  • 摘要:Background

    It is controversial issue that heparin decreases thrombosis for microsurgical anastomosis, and its effective role is under discussion. This study is for proving whether low-dose heparin is preventing thrombosis in free flap reconstruction.

    Methods

    Through chart reviews of 134 patients, using low-dose heparin for free tissue transfer from 2011 to 2016, retrospective analysis was performed. 33 patients received low-dose heparin therapy after surgery. And 101 patients received no-heparin therapy. Complications included flap necrosis, hematoma formation, dehiscence and infection.

    Results

    In no-heparin therapy group, comparing the flap necrosis revealed 16 cases (15.84%). And, flap necrosis was 6 cases (18.18%) in low-dose heparin therapy group. The statistical analysis of flap necrosis rate showed no significant difference ( p =0.75). The results showed that there was no significant difference of flap necrosis rate between two groups.

    Conclusion

    In this study, patients in the low-dose heparin group had no significantly lower rates of flap failure compared with no-heparin group. This suggests that low-dose heparin may not prevent thrombosis and subsequent flap failure to a significant extent.

  • 关键词:Heparin; Free tissue flaps; necrosis; hematoma
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