Agaricus blazei Murrill has indeed generated a lot of interest in the scientific community. One of the components of mushroom was a polysaccharide complex with a low molecular weight called α-1.4-Glucan, β-1.6-Glucan. The scientists reported that this polysaccharide had the strongest antitumor effect. It was selectively kill tumour cells without affecting normal cells. Mycelian biomass is a sterile grain substrate that has been inoculated and colonized with fungal mycelium. After the substrate is fully cured, it is dried and ground, and then used for chemical determinations. Mycelian biomass contains: residual cereals, fungal mycelium, metabolites and enzymes secreted by fungal mycelium. Mushroom mycelial biomass products contain a wide range of bioactive molecules and key immunomodulating beta-glucans and related hetero-polysaccharides. The beta-glucan levels in the studied mycelial biomass ranging from 1.17% in millet mycelial biomass to 1.79% in grain mycelial biomass.