Infectious and non-infectious liver diseases are the cause of many deaths around the globe. Viral hepatitis is a major public health problem worldwide, with hundreds of millions of infected people and millions of deaths. Following a long-term inflammation, hepatocytes begin to die, to necrosis and liver cirrhosis is installed. The consequences of cirrhosis are serious, involving ascites, brain dysfunction, gastric or esophageal haemorrhage and even hepatocellular carcinoma. Apart from viral hepatitis, the hepatic function is also affected by a number of non-infectious, chronic diseases, some of which are unspecified. Our study looked at the use of laboratory TBil (bilirubin) and DBil (direct bilirubin) in the monitoring of patients suffering from chronic hepatitis, unspecified and non-infectious hepatitis, hospitalized in the Pitesti County Emergency Hospital in 2014. They come from urban and rural areas and their age is between 18 and 97 years. Values ​​greater than 1.2 mg/dl of TBil and over 0.52 mg/dl of DBil are recorded in various chronic and unspecified liver diseases. The increase in the values ​​of the two types of bilirubin is observed in both genders. By early diagnosis and by establishing an appropriate treatment, chronic processes can be prevented and treatment costs will not be so great.