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  • 标题:La variante frontale de la maladie d’Alzheimer
  • 作者:Harmony Duclos ; Vincent de La Sayette ; Francis Eustache
  • 期刊名称:Revue de Neuropsychologie Neurosciences Cognitives et Cliniques
  • 印刷版ISSN:2101-6739
  • 电子版ISSN:2102-6025
  • 出版年度:2017
  • 卷号:9
  • 期号:4
  • 页码:237-242
  • DOI:10.1684/nrp.2017.0434
  • 出版社:John Libbey Eurotext
  • 摘要:Atypical forms of Alzheimer's disease (AD) have been described for a long time, but it is only recently that language, frontal and visuospatial variants have been incorporated into the clinical diagnosis and research criterion of AD. It is now possible to establish an in vivo diagnosis of frontal variant of AD (fv-AD) with a high degree of probability thanks to the association between neuropsychological profile and biomarkers. However, the neuropsychological and behavioral profiles of patients with fv-AD are still poorly understood, sometimes leading to misdiagnosis, especially with the behavioral variant of frontotemporal lobar degeneration (bv-FTLD). Social cognition assessment seems to be a promising tool for the differential diagnosis between fv-AD, AD and bv-FTLD.
  • 关键词:frontal variant of Alzheimer's disease; differential diagnosis; behavioral disturbances; executive disturbances; social cognition
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