摘要：Objectives. To evaluate 2-year changes in soda consumption, weight, and waist circumference. Methods. We followed 11 218 women from the Mexican Teachers’ Cohort from 2006 to 2008. Dietary data were collected using a semiquantitative food frequency questionnaire. Weight was self-reported, and waist circumference was self-measured. We used linear regression to evaluate changes in sugar-sweetened and sugar-free soda consumption in relation to changes in weight and waist circumference, adjusting for lifestyle and other dietary factors. Results. Compared with no change, a decrease in sugar-sweetened soda consumption by more than 1 serving per week was associated with less weight gain (−0.4 kg; 95% confidence interval [CI] = −0.6, −0.2). Conversely, relative to no change, an increase in sugar-sweetened soda by more than 1 serving per week was associated with a 0.3-kilogram (95% CI = 0.2, 0.5) increase in weight. An increase of 1 serving per day of sugar-sweetened soda was associated with a 1.0 kg (95% CI = 0.7, 1.2; P < .001) increase in weight. The results for waist circumference were similar. Conclusions. Moderate changes in consumption of sugar-sweetened soda over a 2-year period were associated with corresponding changes in weight and waist circumference among Mexican women. In the era of the global obesity epidemic, identifying effective policies aimed at preventing weight gain has become a priority. Growing evidence has shown that consumption of sugar-sweetened beverages is associated with weight gain and increased risk of obesity. 1 Reducing consumption of these beverages in the population is currently regarded as a key component of any comprehensive obesity prevention strategy. 2,3 Because new evidence from Mexico 4 and the United States 5 has shown that excise taxes on sugar-sweetened beverages affect sales and lower consumption of these beverages shortly after their introduction, it is important to understand the medium-term impact of changes in sugar-sweetened beverage consumption on weight. Previous experimental and observational studies on sugar-sweetened beverage intake and weight may not have directly addressed the effects of changes in beverage intake when considering population-level policies. Two recent randomized trials on sugar-sweetened beverages relied on highly selected populations of children and obese and overweight adults. 6,7 Moreover, most prospective observational studies have evaluated baseline sugar-sweetened beverage consumption and its association with weight gain instead of changes in sugar-sweetened beverage consumption. 8 Evaluating changes in sugar-sweetened beverage intake on changes in adiposity in a population-based study may more appropriately address the temporal relation between limiting sugar-sweetened beverage consumption and adiposity in the general population. We used data from an ongoing large prospective study in Mexico that uniquely assessed diet on 2 occasions in a 2-year period to investigate the relation between changes in sugar-sweetened and sugar-free soda consumption and changes in body weight and waist circumference in women.
