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  • 标题:The Neuroprotective Effects of Phenolic Acids: Molecular Mechanism of Action
  • 本地全文:下载
  • 作者:Dominik Szwajgier ; Kamila Borowiec ; Katarzyna Pustelniak
  • 期刊名称:Nutrients
  • 电子版ISSN:2072-6643
  • 出版年度:2017
  • 卷号:9
  • 期号:5
  • 页码:477
  • DOI:10.3390/nu9050477
  • 语种:English
  • 出版社:MDPI Publishing
  • 摘要:The neuroprotective role of phenolic acids from food has previously been reported by many authors. In this review, the role of phenolic acids in ameliorating depression, ischemia/reperfusion injury, neuroinflammation, apoptosis, glutamate-induced toxicity, epilepsy, imbalance after traumatic brain injury, hyperinsulinemia-induced memory impairment, hearing and vision disturbances, Parkinson’s disease, Huntington’s disease, anti-amyotrophic lateral sclerosis, Chagas disease and other less distributed diseases is discussed. This review covers the in vitro, ex vivo and in vivo studies concerning the prevention and treatment of neurological disorders (on the biochemical and gene expression levels) by phenolic acids.
  • 关键词:cinnamic acids; benzoic acids; polyphenols; neuroprotection; neuroinflammation; central nervous system; neuron; glial cell; neurological disorder cinnamic acids ; benzoic acids ; polyphenols ; neuroprotection ; neuroinflammation ; central nervous system ; neuron ; glial cell ; neurological disorder
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