The purpose of this study was to examine the level of sense of coherence (SOC) and its factors in middle aged-women according to their age group: young-middle women (45–54) and old-middle women (55–64). The participants were middle-aged women who live in Tokyo ( N =328). Similar to the national average, the old middle-aged women had a significantly higher SOC score than the young middle-aged women. As the result of multiple regression analysis, through middle-aged women “generativity” and “circumstances” were related to SOC. Thus, “the number of opportunities for intergenerational” in the young-middle and “having job or not” in the old-middle women were related to SOC.