标题:Reconstructing Tone Sequences from Functional Magnetic Resonance Imaging Blood-Oxygen Level Dependent Responses within Human Primary Auditory Cortex
摘要:Here we show that, using fMRI BOLD responses in human primary auditory cortex (PAC), it is possible to reconstruct the sequence of auditory frequencies that a person has been listening to over time. First, we characterized the tonotopic organization of each subject’s auditory cortex by measuring auditory responses to randomized pure tone stimuli and modeling the frequency tuning of each fMRI voxel as a Gaussian in log frequency space. Then, we tested our model by examining its ability to work in reverse. Auditory responses were re-collected in the same subjects, except this time they listened to sequences of frequencies taken from simple songs (e.g., “Somewhere Over the Rainbow”). By finding the frequency that minimized the difference between the model’s prediction of BOLD responses and actual BOLD responses, we were able to reconstruct tone sequences, with mean frequency estimation errors of half an octave or less, with little evidence of systematic biases.
关键词:auditory; Decoding; Population receptive field; tonotopy; primary auditory cortex