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  • 标题:Morphopathological and immunohistochemical features of a pure mucinous breast carcinoma – Case report
  • 本地全文:下载
  • 作者:Mariana Aschie ; Gabriela Izabela Baltatescu ; Georgeta Camelia Cozaru
  • 期刊名称:ARS Medica Tomitana
  • 电子版ISSN:1841-4036
  • 出版年度:2016
  • 卷号:22
  • 期号:3
  • 页码:174-180
  • DOI:10.1515/arsm-2016-0029
  • 语种:English
  • 出版社:Walter de Gruyter GmbH
  • 摘要:Pure mucinous carcinoma is a rare special type of breast carcinoma with a 2% incidence and it is usualy asociated with a good prognosis. It must distingished from the mixed subtype of mucinos breast carcinoma, which has an invasive non-mucinous component in more than 10% of the tumor and change the favourable outcome of the first subtype. In this report we present a case of a premenopausal woman with a lump in right breast wich histopathologically proved to be a pure mucinous carcinoma associated with high grade ductal carcinoma in situ. Immunohistochemical and ancillary studies demonstrate a great heterogeneity of the neoplastic cells, with different molecular profile for each component of the tumor. The presence of ductal carcinoma in situ with a different imunophenotype from pure mucinous carcinoma rise the ipothesis of a different tumor cell biology which may change clincal evolution.
  • 关键词:Pure mucinous breast carcinoma ; ductal carcinoma in situ ; immunohistochemistry ; CISH
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