Factors that determinated phytosanitarian chernozems worsening was examined in the space between Prut and Nistru in the global phenomenon of agricultural soil exhaustion. It was established anthropological and natural origin (pedofunctional) phenomenon of studied exhaustion chernozems exhaustion. The main cause of cernozems exhaustion is to reduce the dominant role of the training and accumulation of humus. Through this prism of ideas, soil exhaustion and phytosanitarian worsening is inherent to agricultural system currently practiced. The impact mitigating of this process involves the bioenergy resources sustainable management involved in anthropogenic pedogenesis.