The purpose of the present study was to investigate features and the structure of life skills in persons with high levels of sense of coherence (SOC). Welch's t -test indicated that the persons with the higher level of SOC showed higher life skills in planning, knowledge summarization, self-esteem, positive thinking, intimacy, and leadership than those with a lower level of SOC. Moreover, hierarchical cluster analysis by Ward method and structural equation modeling suggested that persons with the higher level of SOC showed life skills with a consistent hierarchical structure.