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  • 标题:Mass Spectrometry as a Tool to Enhance “-omics” Education †
  • 本地全文:下载
  • 作者:Michael J. Wolyniak ; Nathan S. Reyna ; Ruth Plymale
  • 期刊名称:Journal of Microbiology and Biology Education
  • 印刷版ISSN:1935-7877
  • 电子版ISSN:1935-7885
  • 出版年度:2018
  • 卷号:19
  • 期号:1
  • 页码:1-2
  • DOI:10.1128/jmbe.v19i1.1459
  • 出版社:American Society for Microbiology
  • 摘要:The rise of "-omics" related technologies makes it essential for students to have experience working with large bioinformatics data sets. Although”-omic” datasets are complex and abstract, effective instruction can be improved when students see the direct connections between the data on a computer screen and the results of "wet lab" experimentation. Here we describe the use of protein mass spectrometry as a means for students to gain experience in connecting bioinformatic data with work done at the lab bench. Course-based Research Experiences (CREs) based on these techniques are accessible to institutions of all types as a result of rapidly declining costs for whole genome and proteome analysis. Our implementation is within a CRE based on viral infection of a bacterial host; however, this basic paradigm may be applied to other experimental systems of interest.
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