期刊名称:Journal of Microbiology and Biology Education
印刷版ISSN:1935-7877
电子版ISSN:1935-7885
出版年度:2018
卷号:19
期号:1
页码:1-2
DOI:10.1128/jmbe.v19i1.1459
出版社:American Society for Microbiology
摘要:The rise of "-omics" related technologies makes it essential for students to have experience working with large bioinformatics data sets. Although”-omic” datasets are complex and abstract, effective instruction can be improved when students see the direct connections between the data on a computer screen and the results of "wet lab" experimentation. Here we describe the use of protein mass spectrometry as a means for students to gain experience in connecting bioinformatic data with work done at the lab bench. Course-based Research Experiences (CREs) based on these techniques are accessible to institutions of all types as a result of rapidly declining costs for whole genome and proteome analysis. Our implementation is within a CRE based on viral infection of a bacterial host; however, this basic paradigm may be applied to other experimental systems of interest.