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文章基本信息

  • 标题:Skeletal muscle regeneration is modulated by inflammation
  • 本地全文:下载
  • 作者:Wenjun Yang ; Ping Hu
  • 期刊名称:Journal of Orthopaedic Translation
  • 印刷版ISSN:2214-031X
  • 出版年度:2018
  • 卷号:13
  • 页码:25-32
  • DOI:10.1016/j.jot.2018.01.002
  • 出版社:Elsevier B.V.
  • 摘要:

    Skeletal muscle regeneration is a complex process orchestrated by multiple steps. Recent findings indicate that inflammatory responses could play central roles in bridging initial muscle injury responses and timely muscle injury reparation. The various types of immune cells and cytokines have crucial roles in muscle regeneration process. In this review, we briefly summarise the functions of acute inflammation in muscle regeneration.

    The translational potential of this article

    Immune system is closely relevant to the muscle regeneration. Understanding the mechanisms of inflammation in muscle regeneration is therefore critical for the development of effective regenerative, and therapeutic strategies in muscular disorders. This review provides information for muscle regeneration research regarding the effects of inflammation on muscle regeneration.

  • 关键词:Chronic muscle disorders ; Cytokines ; Immune cells ; Inflammation ; Muscle regeneration ; Muscle stem cells
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