期刊名称：Annals of Agricultural and Environmental Medicine
印刷版ISSN：1232-1966
电子版ISSN：1898-2263
出版年度：2017
卷号：24
期号：2
页码：265-270
DOI：10.26444/aaem/74597
出版社：Institute of Agricultural Medicine in Lublin
摘要：Introduction. There is a lack in the worldwide literature of reports on the Neuromarkers of Post-Traumatic Stress Disorder(PTSD) in patients after bilateral hand amputation The aim of this study was to test a hypothesis regarding developingPost-Traumatic Stress Disorder (PTSD) in a patient after bilateral hand amputation with the use of Event Related Potentials(ERPs). On the basis of previous research, the amplitudes of P3 ERP components elicited in the cued GO/NOGO tasks havebeen chosen as candidates for neuromarkers of PTSD.Case study. A 24-year-old patient had undergone bilateral hand amputation 12 months previously. The patient wasrepeatedly operated on (he had undergone successful bilateral hand replantation) and despite the severity of the injuries,he recovered. However, the patient complained of flashbacks, anxiety and sleep difficulties. Specialist tests showed thepresence of PTSD. The patient participated in the cued GO/NOGO task (Kropotov, 2009) with recording 19-channel EEG. P3GO and NOGO waves in this task were found to be significantly smaller, in comparison to a group of healthy control subjectsof the same age (N=23) taken from the HBI normative database (https://www.hbimed.com/). This observed pattern of ERPwaves in the patient corresponds to the pattern found in PTSD patients.Conclusions. ERPs in a GO/NOGO task can be used in the assessment of the functional brain changes induced by chronic PTSD.
