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  • 标题:Training replicable predictors in multiple studies
  • 本地全文:下载
  • 作者:Prasad Patil ; Giovanni Parmigiani
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:2018
  • 卷号:115
  • 期号:11
  • 页码:2578-2583
  • DOI:10.1073/pnas.1708283115
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:This article considers replicability of the performance of predictors across studies. We suggest a general approach to investigating this issue, based on ensembles of prediction models trained on different studies. We quantify how the common practice of training on a single study accounts in part for the observed challenges in replicability of prediction performance. We also investigate whether ensembles of predictors trained on multiple studies can be combined, using unique criteria, to design robust ensemble learners trained upfront to incorporate replicability into different contexts and populations.
  • 关键词:ensemble learning ; replicability ; cross-study validation ; machine learning ; validation
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