出版社：International Medical Journal Management and Indexing System
摘要：Studies to date have shown the contribution of an athletes genetic endowment in athletic performance. Although these studies revealed that cognitive abilities influence athletes competitive performance, there are only a few studies trying to investigate the association between genetic polymorphisms, which is associated with cognitive ability, and athletic performance. In the present study, we aimed investigate the link between dopamine receptor-2 (DRD2) gene rs1800497 polymorphism, which is known to exert influences on brain dopaminergic system and athletic performance of volleyball players and bodybuilders. In this regard, we enrolled 9 female volleyball players and 15 active bodybuilders in the study. Real-time PCR methodology was used for genotyping. The respective numbers and percentages of A1A1, A1A2 and A2A2 genotypes in bodybuilders were 2 (13%), 1 (7%) and 12 (80%). All the volleyball players had A2A2 genotypes. The results have revealed that addiction related A1 allele is underrepresented in volleyball players and bodybuilders. These first findings indicate that the polygenic or multifactorial mechanism may explain effect of cognitive abilities in athletes performance.
