摘要：Background and Objective: A global epidemic increase in obesity prevalence has been observed in most of the countries. This phenomenon is an emerging health problem that is associated with increasing prevalence of obesity-related co-morbidities. This study sought to investigate whether a pro-thrombotic state is related to anthropometric parameters in a student population. Materials and Methods: Forty young adult females aged 20-30 years (mean age: 21.0±3.04 years) were included in the study. Participants were sub-divided into three groups: The lean (n = 12) group, which included individuals with a body mass index (BMI) between 18 and 24.9 kg m2, the overweight/obese (n = 16) group, which included individuals with a BMI > 25 kg m2 and the obese diabetic group (n = 16), which included individuals with a BMI > 30 kg m2 and diabetes mellitus (DM). Anthropometric measurements, including BMI, waist circumference (WC), hip circumference (HC) and the waist/hip (W/H) ratio were determined and calculated in this study and hemostatic metrics were assessed. Results: The mean prothrombin times (PTs) were 11.9±0.9, 11.2±0.4 and 11.7±0.9 sec in the lean, overweight/obese and obese diabetic groups, respectively. The examined groups exhibited a negative correlation between PT and BMI (r = -0.4, p = 0.06) and a positive correlation between PT and W/H ratio (r = 0.5, p = 0.04). No other significant correlations between BMI or W/H ratio and other hematological indices were observed. Conclusion: Obesity could be associated with hemostatic changes that favor the development of thrombosis, this possibility highlights the need for the implementation of preventative measures.
